GSDMD antibody

GSDMD is a member of the gasdermin family. Members of this family appear to play a role in regulation of epithelial proliferation. GSDMD has been suggested to act as a tumor suppressor. Recently, GSDMD is identified as a new component of inflammasomes, and it is an executor of pyroptosis and required for interleukin-1β secretion. Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death.

Gasdermin-D|Gasdermin domain-containing protein 1|Gasdermin-D, C-terminal (GSDMD-CT, hGSDMD-CTD) |Gasdermin-D, p13|Gasdermin-D, 13 kDa (13 kDa GSDMD) |Gasdermin-D, p40|GSDMD|DFNA5L|GSDMDC1