DSPC

DSPC (1,2-Distearoyl-sn-glycero-3-phosphorylcholine) is a cylindrical-shaped lipid. DSPC is used to synthesize liposomes, and is the lipid component in the lipid nanoparticle (LNP) system[1][2].

Product Specifications

CAS Number

[816-94-4]

Product Name Alternative

1,2-Distearoyl-sn-glycero-3-PC; 1,2-Distearoyl-sn-glycero-3-phosphorylcholine

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H335

Target

Liposome

Type

Oligonucleotides

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/1-2-distearoyl-sn-glycero-3-phosphorylcholine.html

Purity

99.95

Solubility

Ethanol : 12.5 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=P([O-])(OCC[N+](C)(C)C)OC[C@@H](COC(CCCCCCCCCCCCCCCCC)=O)OC(CCCCCCCCCCCCCCCCC)=O

Molecular Formula

C44H88NO8P

Molecular Weight

790.15

Precautions

H302, H315, H319, H335

References & Citations

[1]Andrew D Miller. Delivery of RNAi therapeutics: work in progress. Expert Rev Med Devices. 2013 Nov;10 (6) :781-811.|[2]Jayesh A Kulkarni, et al. On the role of helper lipids in lipid nanoparticle formulations of siRNA. Nanoscale. 2019 Nov 21;11 (45) :21733-21739.