Iduronate 2-sulfate

Product Specifications

CAS Number

[89846-17-3]

UNSPSC Description

Iduronate 2-sulfate (IdOA(2S)) is critically important for the anticoagulant activity. Iduronate 2-sulfate (IdOA(2S)) residue is commonly found in heparan sulfate and heparin[1].

Target Antigen

Others

Type

Reference compound

Related Pathways

Others

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/iduronate-2-sulfate.html

Smiles

O[C@@H]([C@H](O)[C@@H](O)C(O)=O)[C@H](C=O)O[S](=O)(O)=O

Molecular Weight

274.20

References & Citations

[1]Po-Hung Hsieh, et al. Chemoenzymatic synthesis and structural characterization of 2-O-sulfated glucuronic acid-containing heparan sulfate hexasaccharides. Glycobiology. 2014 Aug;24(8):681-92.|[2]Heather N Bethea, et al. Redirecting the substrate specificity of heparan sulfate 2-O-sulfotransferase by structurally guided mutagenesis. Proc Natl Acad Sci U S A. 2008 Dec 2;105(48):18724-9.