DETA NONOate

DETA NONOate (NOC 18) is an exogenous nitric oxide (NO) donor. DETA NONOate shows a slow release normal amounts of NO and long-acting[1][2].

Product Specifications

CAS Number

[146724-94-9]

Product Name Alternative

Diethylamine NONOate; NOC-18

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H335

Target

NO Synthase

Type

Reference compound

Related Pathways

Immunology/Inflammation

Applications

COVID-19-immunoregulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/noc-18.html

Purity

98.10

Solubility

H2O : 50 mg/mL (ultrasonic)

Smiles

O=NN(O)N(CCN)CCN

Molecular Formula

C4H13N5O2

Molecular Weight

163.18

Precautions

H302, H315, H319, H335

References & Citations

[1]Soichiro Sonoda, et al. Exogenous nitric oxide stimulates the odontogenic differentiation of rat dental pulp stem cells. Sci Rep. 2018 Feb 21;8 (1) :3419.|[2]S Shibuta, et al. A new nitric oxide donor, NOC-18, exhibits a nociceptive effect in the rat formalin model. EJ Neurol Sci. 1996 Sep 15;141 (1-2) :1-5|[3]Nandanwar N, et al. Growth medium and nitric oxide alter Mycobacterium abscessus morphotype and virulence. Microbiol Res. 2021 Dec;253:126887. |[4]Umbrasas D, et al. Nitric Oxide Donor NOC-18-Induced Changes of Mitochondrial Phosphoproteome in Rat Cardiac Ischemia Model. Medicina (Kaunas) . 2019 Sep 24;55 (10) :631.