M-PEG5-Propyne
M-PEG5-Propyne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. m-PEG5-Propyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Product Specifications
CAS Number
[1101668-41-0]
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H335
Target
PROTAC Linkers
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/m-peg5-propyne.html
Purity
95.95
Solubility
10 mM in DMSO
Smiles
COCCOCCOCCOCCOCCOCC#C
Molecular Formula
C14H26O6
Molecular Weight
290.35
Precautions
H302, H315, H319, H335
References & Citations
[1]Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27 (8) :998-1006.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, stored under nitrogen, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PEG Linkers
Available Sizes
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