Aminooxy-PEG1-propargyl

Product Specifications

UNSPSC Description

Aminooxy-PEG1-propargyl is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1]. Aminooxy-PEG1-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Target Antigen

PROTAC Linkers

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/aminooxy-peg1-propargyl.html

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

NOCCOCC#C

Molecular Weight

115.13

References & Citations

[1]Zhang F, et al. Discovery of a new class of PROTAC BRD4 degraders based on a dihydroquinazolinone derivative and lenalidomide/pomalidomide. Bioorg Med Chem. 2020 Jan 1;28(1):115228.

Shipping Conditions

Room Temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-140056/Aminooxy-PEG1-propargyl-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-140056/Aminooxy-PEG1-propargyl-SDS-MedChemExpress.pdf

Clinical Information

No Development Reported

CAS Number

1895922-69-6

Available Sizes

Curated Selection

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