Aminooxy-PEG1-propargyl
Product Specifications
UNSPSC Description
Aminooxy-PEG1-propargyl is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1]. Aminooxy-PEG1-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Target Antigen
PROTAC Linkers
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/aminooxy-peg1-propargyl.html
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
NOCCOCC#C
Molecular Weight
115.13
References & Citations
[1]Zhang F, et al. Discovery of a new class of PROTAC BRD4 degraders based on a dihydroquinazolinone derivative and lenalidomide/pomalidomide. Bioorg Med Chem. 2020 Jan 1;28(1):115228.
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-140056/Aminooxy-PEG1-propargyl-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-140056/Aminooxy-PEG1-propargyl-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
1895922-69-6
Available Sizes
Curated Selection
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