Prilocaine (hydrochloride)

Prilocaine hydrochloride, an amino amide, is a Na/K-ATPase inhibitor. Prilocaine has neurotoxic effects[1][2].

Product Specifications

CAS Number

[1786-81-8]

UNSPSC

12352005

Hazard Statement

H315-H319-H320

Target

Na+/K+ ATPase

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/prilocaine-hydrochloride.html

Solubility

10 mM in DMSO

Smiles

CC(NCCC)C(NC1=CC=CC=C1C)=O.Cl

Molecular Formula

C13H21ClN2O

Molecular Weight

256.77

Precautions

P264-P280-P302+P352-P305+P351+P338-P362

References & Citations

[1]M Mete, et al. Neurotoxic effects of local anesthetics on the mouse neuroblastoma NB2a cell line. Biotech Histochem. 2015 Apr;90 (3) :216-22.|[2]H Kutchai, et al. Effects of local anaesthetics on the activity of the Na, K-ATPase of canine renal medulla. Pharmacol Res. 2000 Jan;41 (1) :1-7.