CC-885-CH2-PEG1-NH-CH3
CC-885-CH2-PEG1-NH-CH3 is a neoDegrader that can be used in the synthesis of Antibody neoDegrader Conjugate (AnDC) . CC-885-CH2-PEG1-NH-CH3 is the toxic molecule of ADC, which can specifically degrade the target protein in cancer cells through the E3 ubiquitin ligase pathway[1].
Product Specifications
CAS Number
[2722698-03-3]
UNSPSC
12352203
Hazard Statement
H302, H315, H319, H335
Target
ADC Payload; E3 Ligase Ligand-Linker Conjugates
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related; PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/cc-885-ch2-peg1-nh-ch3.html
Purity
99.22
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(NCC1=CC=C2C(N(C3C(NC(CC3)=O)=O)CC2=C1)=O)NC4=CC=C(CCOCCNC)C(Cl)=C4
Molecular Formula
C26H30ClN5O5
Molecular Weight
528.00
Precautions
H302, H315, H319, H335
References & Citations
[1]FISHKIN N, et, al. Neodegrader conjugates. WO2021198965A1.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
ADC Related
Clinical Information
No Development Reported
Available Sizes
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