HMRG
HMRG is a type of hydroxymethyl rhodamine green fluorescent scaffold, featuring an open non-cyclic structure. HMRG can produce significant dynamic fluorescence changes through a one-step enzymatic reaction at physiological pH, which is useful for developing various probes. Fluorescent probes based on HMRG can be used for fluorescence detection of diseases such as tumors and diabetic nephropathy[1].
Product Specifications
CAS Number
1629965-68-9
UNSPSC
12171500
Target
Fluorescent Dye
Type
Dye Reagents
Related Pathways
Others
Field of Research
Cancer; Endocrinology
Assay Protocol
https://www.medchemexpress.com/hmrg.html
Smiles
N=C1C=CC2=C(C3=C(CO)C=CC=C3)C4=C(C=C(C=C4)N)OC2=C1
Molecular Formula
C20H16N2O2
Molecular Weight
316.35
References & Citations
[1]Sakabe M, et al. Rational design of highly sensitive fluorescence probes for protease and glycosidase based on precisely controlled spirocyclization. J Am Chem Soc. 2013 Jan 9;135 (1) :409-14.
Shipping Conditions
Room temperature
Scientific Category
Dye Reagents
Clinical Information
No Development Reported
Frequently Asked Questions
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