Maydispenoid B
Maydispenoid B is a potent immunosuppressor. Maydispenoid B can inhibit anti-CD3/anti-CD28 mAbs activated and lipopolysaccharide activated murine splenocyte proliferation[1].
Product Specifications
CAS Number
[3024647-69-3]
UNSPSC
12352005
Target
CD28; CD3
Type
Natural Products
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/maydispenoid-b.html
Solubility
10 mM in DMSO
Smiles
CC1=CC(/C2=C(C(C[C@]3([C@@]4([C@@H](C)C[C@H](/C=C(C)/C)O4)CC[C@@]3(C[C@]12[H])C)[H])=O)\CO)=O
Molecular Formula
C25H34O4
Molecular Weight
398.54
References & Citations
[1]Duan X, et al. New secondary metabolites with immunosuppressive activity from the phytopathogenic fungus Bipolaris maydis. Bioorg Chem. 2020 Jun;99:103816.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Curated Selection
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