Maydispenoid B

Maydispenoid B is a potent immunosuppressor. Maydispenoid B can inhibit anti-CD3/anti-CD28 mAbs activated and lipopolysaccharide activated murine splenocyte proliferation[1].

Product Specifications

CAS Number

[3024647-69-3]

UNSPSC

12352005

Target

CD28; CD3

Type

Natural Products

Related Pathways

Immunology/Inflammation

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/maydispenoid-b.html

Solubility

10 mM in DMSO

Smiles

CC1=CC(/C2=C(C(C[C@]3([C@@]4([C@@H](C)C[C@H](/C=C(C)/C)O4)CC[C@@]3(C[C@]12[H])C)[H])=O)\CO)=O

Molecular Formula

C25H34O4

Molecular Weight

398.54

References & Citations

[1]Duan X, et al. New secondary metabolites with immunosuppressive activity from the phytopathogenic fungus Bipolaris maydis. Bioorg Chem. 2020 Jun;99:103816.