GSK878
Product Specifications
UNSPSC Description
GSK878 is a highly potent, long-acting HIV-1 inhibitor with the EC50 of 39 pM[1].
Target Antigen
HIV
Type
Reference compound
Related Pathways
Anti-infection
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/gsk878.html
Smiles
O=C1N(C2=CC=C(Cl)C3=C2N(C)N=C3NS(C)(=O)=O)C([C@@H](NC(CN4C(C(F)(F)[C@@]5([H])[C@]6([H])C5)=C6C(C(F)F)=N4)=O)CC7=CC(F)=CC(F)=C7)=NC8=C1C=CC(N9C[C@H](C)O[C@H](C)C9)=C8
Molecular Weight
918.31
References & Citations
[1]Gillis EP, et al. Potent Long-Acting Inhibitors Targeting the HIV-1 Capsid Based on a Versatile Quinazolin-4-one Scaffold. J Med Chem. 2023;66(3):1941-1954.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-153782/GSK878-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-153782/
Clinical Information
No Development Reported
CAS Number
2417048-11-2
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