BR102910

BR102910 is a selective fibroblast activation protein (FAP) inhibitor with the IC50 of 2 nM. BR102910 also inhibits prolyl oligopeptidase (PREP) with the IC50 of 49.00 μM. BR102910 can be used for the researchof type 2

Product Specifications

CAS Number

[2505339-54-6]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Prolyl Endopeptidase (PREP)

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/br102910.html

Purity

99.82

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(C1=CSC(CC2=CC=C(Cl)C(Cl)=C2)=N1)NCC(N3[C@H](C#N)CC(F)(F)C3)=O

Molecular Formula

C18H14Cl2F2N4O2S

Molecular Weight

459.30

Precautions

H302, H315, H319, H335

References & Citations

[1]Hui Jin Jung, et al. Identification of BR102910 as a selective fibroblast activation protein (FAP) inhibitor. Bioorg Med Chem Lett. 2021 Apr 1;37:127846.