GJ103 (sodium)
GJ103 sodium is a read-through compound that can induce read through of premature stop codons. GJ103 sodium has potential for the research of genetic disorders caused by nonsense mutations[1].
Product Specifications
CAS Number
1459687-96-7
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
DNA/RNA Synthesis
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Field of Research
Cancer; Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/gj103-sodium.html
Purity
99.46
Solubility
DMSO : 50 mg/mL (ultrasonic) |H2O : ≥ 10 mg/mL
Smiles
O=C(O[Na])CSC1=NN=C(C2=NC=CC=C2)N1C3=CC=CC(OC)=C3
Molecular Formula
C16H13N4NaO3S
Molecular Weight
364.35
Precautions
H302, H315, H319, H335
References & Citations
[1]Du L, et al. A new series of small molecular weight compounds induce read through of all three types of nonsense mutations in the ATM gene. Mol Ther. 2013 Sep;21 (9) :1653-60.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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