GJ103 (sodium)

GJ103 sodium is a read-through compound that can induce read through of premature stop codons. GJ103 sodium has potential for the research of genetic disorders caused by nonsense mutations[1].

Product Specifications

CAS Number

[1459687-96-7]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

DNA/RNA Synthesis

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Field of Research

Cancer; Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/gj103-sodium.html

Purity

99.46

Solubility

DMSO : 50 mg/mL (ultrasonic) |H2O : ≥ 10 mg/mL

Smiles

O=C(O[Na])CSC1=NN=C(C2=NC=CC=C2)N1C3=CC=CC(OC)=C3

Molecular Formula

C16H13N4NaO3S

Molecular Weight

364.35

Precautions

H302, H315, H319, H335

References & Citations

[1]Du L, et al. A new series of small molecular weight compounds induce read through of all three types of nonsense mutations in the ATM gene. Mol Ther. 2013 Sep;21 (9) :1653-60.