THIIC
THIIC (LY2607540) is a compound with anxiolytic and antidepressant potential. It is a positive allosteric modulator of mGlu receptors, exhibits anxiolytic and antidepressant-like activities in multiple animal models, and can also affect sleep and neurochemical changes.
Product Specifications
CAS Number
1204737-09-6
Product Name Alternative
LY2607540
UNSPSC
12352005
Target
MGluR
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/thiic.html
Smiles
O=C(NCC1=CC=C(C=C1)COC2=CC=C(C(O)=C2C(F)(F)F)C(C(C)C)=O)C3=CN(C=N3)C
Molecular Formula
C24H24F3N3O4
Molecular Weight
475.46
References & Citations
[1]N- (4- ((2- (trifluoromethyl) -3-hydroxy-4- (isobutyryl) phenoxy) methyl) benzyl) -1-methyl-1H-imidazole-4-carboxamide (THIIC), a novel metabotropic glutamate 2 potentiator with potential anxiolytic/antidepressant properties: in vivo profiling suggests a link between behavioral and central nervous system neurochemical changes
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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