SFTI-1
SFTI-1 is a cyclic peptide trypsin inhibitor consisting of 14 amino acid residues. SFTI-1 belongs to the Bowman-Birk class of inhibitors. Characterized by its small size, high stability, and potent activity, SFTI-1 can be used for research on peptide drug design platforms[1][2].
Product Specifications
CAS Number
245080-24-4
UNSPSC
12352209
Target
Ser/Thr Protease
Type
Peptides
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/sfti-1.html
Purity
99.60
Solubility
DMSO : ≥ 100 mg/mL
Smiles
O=C(N(CCC1)[C@]1([H])C(N[C@@](C(N[C@](CSSC[C@@](NC([C@@H](NC2=O)CCCNC(N)=N)=O)([H])C3=O)([H])C(N[C@H](C(N4[C@@](C(N[C@H](C(NC2)=O)CC(O)=O)=O)([H])CCC4)=O)CC5=CC=CC=C5)=O)=O)([H])[C@@H](C)CC)=O)[C@@](CCC6)([H])N6C([C@](NC([C@@H](NC([C@@H](NC([C@](N3)([H])[C@H](O)C)=O)CCCCN)=O)CO)=O)([H])[C@@H](C)CC)=O
Molecular Formula
C67H104N18O18S2
Molecular Weight
1513.78
References & Citations
[1]M L Korsinczky, et al. Solution structures by 1H NMR of the novel cyclic trypsin inhibitor SFTI-1 from sunflower seeds and an acyclic permutant. J Mol Biol. 2001 Aug 17;311 (3) :579-91. |[2]Korsinczky ML, et al. Disulfide bond mutagenesis and the structure and function of the head-to-tail macrocyclic trypsin inhibitor SFTI-1. Biochemistry. 2005 Feb 1;44 (4) :1145-53.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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