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ACI-19626

TDP-43-IN-2 (compound 17) is a TDP-43 inhibitor, and can be used for study of neurodegenerative disease[1].

Product Specifications

CAS Number

[3033951-93-5]

Product Name Alternative

TDP-43-IN-2

UNSPSC

12352005

Target

Amyloid-β

Type

Reference compound

Related Pathways

Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/tdp-43-in-2.html

Purity

98.52

Solubility

DMSO : 5 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=C1C2=C(CCN1C3=CC=CN=C3)N=C(C4=C(F)N=C(N5CCC(CC5)CO)C=C4)S2

Molecular Formula

C22H22FN5O2S

Molecular Weight

439.51

References & Citations

[1]Nicolas Dreyfus, et al. Novel compounds for the diagnosis of tdp-43 proteinopathies. WO2024068948A1. 2024-04-04.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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