PROTAC SMARCA2 degrader-14
Product Specifications
UNSPSC Description
SMARCA2 degrader-3 (compound I-323) is a PROTAC degrader targeting SMARCA2; it degrades SMARCA2 proteins in A549 cells with an DC50 90 after 24 h of treatment[1].
Target Antigen
PROTACs
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/protac-smarca2-degrader-14.html
Smiles
O=C1NC(C(CC1)N2C(C3=CC=C(NC4CCC(CC4)N5CCC(CC5)N6N=CC(C7=C(N)N=NC(C8=C(O)C=CC=C8)=C7)=C6)C=C3C2=O)=O)=O
Molecular Weight
689.76
References & Citations
[1]Preparation of heterocyclic compounds as SMARCA degraders and uses thereof. World Intellectual Property Organization, WO2020251971 A1 2020-12-17.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-163866/PROTAC-SMARCA2-degrader-14-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-163866/
Clinical Information
No Development Reported
CAS Number
2568276-73-1
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS1264804-01 0.02 mg (E-Coli)
Recombinant Rhesus papillomavirus type 1 Protein E6 (E6)
Ask
View Details 
MBS1264804-02 0.1 mg (E-Coli)
Recombinant Rhesus papillomavirus type 1 Protein E6 (E6)
Ask
View Details MBS1264804-03 0.02 mg (Yeast)
Recombinant Rhesus papillomavirus type 1 Protein E6 (E6)
Ask
View Details MBS1264804-04 0.1 mg (Yeast)
Recombinant Rhesus papillomavirus type 1 Protein E6 (E6)
Ask
View Details