Etigilimab
Etigilimab (OMP-313M32), a humanized IgG1 monoclonal antibody, blocks TIGIT interaction with PVR (CD155; poliovirus receptor) and inhibits downstream signalling with target cell killing[1].
Product Specifications
CAS Number
[2044984-83-8]
Product Name Alternative
OMP-313M32
UNSPSC
12352203
Target
Others
Type
Inhibitory Antibodies
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/etigilimab.html
Purity
99.26
Solubility
10 mM in DMSO
Smiles
[Etigilimab]
Molecular Weight
(144.84 kDa)
References & Citations
[1]Meredith McKean, et al. Safety and efficacy of etigilimab in combination with nivolumab in select recurrent/advanced solid tumors.
Shipping Conditions
Dry Ice
Storage Conditions
Store at -80°C for 2 years
Scientific Category
Inhibitory Antibodies
Clinical Information
Phase 2
Available Sizes
Curated Selection
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