CMD178 (TFA)
CMD178 TFA is a lead peptide that consistently reduced the expression of Foxp3 and STAT5 induced by IL-2/s IL-2Rα signaling and inhibits Treg cell development[1].
Product Specifications
UNSPSC
12352209
Target
STAT
Type
Peptides
Related Pathways
JAK/STAT Signaling; Stem Cell/Wnt
Applications
COVID-19-immunoregulation
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/cmd178-tfa.html
Purity
99.71
Solubility
H2O : 2.5 mg/mL (ultrasonic)
Smiles
OC(C(F)(F)F)=O.F[R](F)[K].[Y]OCC1=CC=CC=C1
Molecular Formula
C48H60F3N9O9
Molecular Weight
964.05
References & Citations
[1]Price-Troska T, et, al. Inhibiting IL-2 signaling and the regulatory T-cell pathway using computationally designed peptides. Invest New Drugs. 2019 Feb;37 (1) :9-16.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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