Xylocydine
Product Specifications
UNSPSC Description
Xylocydine is an inhibitor of CDK1/2, inhibiting CDK function in various apoptotic processes. Xylocydine specifically blocks CDK1 and CDK2 activity with IC50 of 1.4 nM and 61 nM, respectively. In addition, Xylocydine downregulates phosphorylated nucleolin and retinoblastoma protein levels.[1].
Target Antigen
CDK
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-Kinase/protease
Field of Research
cancer
Assay Protocol
https://www.medchemexpress.com/xylocydine.html
Smiles
O=C(N)C1=C(N([C@H]2O[C@@H](CO)[C@@H](O)[C@@H]2O)C3=NC=NC(N)=C31)Br
Molecular Weight
388.17
References & Citations
[1]Xylocydine, a Novel Inhibitor of Cyclin-Dependent Kinases, Prevents the Tumor Necrosis Factor-Related ApoptosisInducing Ligand-Induced Apoptotic Cell Death of SK-HEP-1 Cells
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-118310/Xylocydine-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-118310/
Clinical Information
No Development Reported
CAS Number
685901-63-7
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