Buspirone (hydrochloride)

Buspirone hydrochloride is a 5-HT1A receptor agonist. Buspirone hydrochloride can be used for anxiety and depression research[1][2].

Product Specifications

CAS Number

[33386-08-2]

UNSPSC

12352005

Hazard Statement

H301

Target

5-HT Receptor; Reactive Oxygen Species (ROS)

Type

Reference compound

Related Pathways

GPCR/G Protein; Immunology/Inflammation; Metabolic Enzyme/Protease; Neuronal Signaling; NF-κB

Applications

Neuroscience-Neuromodulation

Field of Research

Cancer; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/Buspirone-hydrochloride.html

Purity

99.99

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

O=C(N(CCCCN1CCN(C2=NC=CC=N2)CC1)C(C3)=O)CC43CCCC4.[H]Cl

Molecular Formula

C21H32ClN5O2

Molecular Weight

421.96

Precautions

H301

References & Citations

[1]Salimi A, et, al. Analysis of Toxicity Effects of Buspirone, Cetirizine and Olanzapine on Human Blood Lymphocytes: in Vitro Model. Curr Clin Pharmacol. 2018;13 (2) :120-127.|[2]Kim JK, et, al. Buspirone alleviates anxiety, depression, and colitis; and modulates gut microbiota in mice. Sci Rep. 2021 Mar 17;11 (1) :6094.