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SF2312

Product Specifications

Product Name Alternative

CGS 10746

UNSPSC Description

SF2312, a natural phosphonate antibiotic (Antibiotic), is a highly potent Enolase inhibitor with IC50s of 37.9 nM and 42.5 nM for human recombinant ENO1 and ENO2, respectively. SF2312 is active against bacteria under anaerobic conditions[1].

Target Antigen

Antibiotic; Bacterial; Enolase

Type

Reference compound

Related Pathways

Anti-infection;Metabolic Enzyme/Protease

Field of Research

Cancer; Infection

Assay Protocol

https://www.medchemexpress.com/sf2312.html

Purity

95.0

Solubility

H2O : 125 mg/mL (ultrasonic)

Smiles

O=C1N(C(CC1P(O)(O)=O)O)O

Molecular Weight

197.08

References & Citations

[1]Paul G Leonard, et al. SF2312 is a natural phosphonate inhibitor of enolase. Nat Chem Biol. 2016 Dec;12(12):1053-1058.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-117778/SF2312-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-117778/SF2312-SDS-MedChemExpress.pdf

Clinical Information

No Development Reported

CAS Number

107729-45-3

Available Sizes

Curated Selection

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