SF2312
SF2312, a natural phosphonate antibiotic (Antibiotic), is a highly potent Enolase inhibitor with IC50s of 37.9 nM and 42.5 nM for human recombinant ENO1 and ENO2, respectively. SF2312 is active against bacteria under anaerobic conditions[1].
Product Specifications
CAS Number
[107729-45-3]
Product Name Alternative
CGS 10746
UNSPSC
12352005
Hazard Statement
H315, H318, H335
Target
Antibiotic; Bacterial; Enolase
Type
Reference compound
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Infection
Assay Protocol
https://www.medchemexpress.com/sf2312.html
Purity
95.0
Solubility
DMSO : 10 mg/mL (ultrasonic) |H2O : 125 mg/mL (ultrasonic)
Smiles
O=C1N(C(CC1P(O)(O)=O)O)O
Molecular Formula
C4H8NO6P
Molecular Weight
197.08
Precautions
H315, H318, H335
References & Citations
[1]Paul G Leonard, et al. SF2312 is a natural phosphonate inhibitor of enolase. Nat Chem Biol. 2016 Dec;12 (12) :1053-1058.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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