CBP/p300-IN-1
CBP/p300-IN-1 is a CBP/EP300 bromodomain inhibitor.
Product Specifications
CAS Number
[2443789-32-8]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Epigenetic Reader Domain
Type
Reference compound
Related Pathways
Epigenetics
Applications
Neuroscience-Neuromodulation
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/CBP-EP300-IN-1.html
Purity
99.71
Solubility
DMSO : 62.5 mg/mL (ultrasonic)
Smiles
CC(N1C2=CC=C(OC)C=C2C(C(NC3=C(F)C=CC(C(OC(C)(C)C)=O)=C3)=O)=C1)=O
Molecular Formula
C23H23FN2O5
Molecular Weight
426.44
Precautions
H302, H315, H319, H335
References & Citations
[1]Xiang Q, et al. Discovery and optimization of 1- (1H-indol-1-yl) ethanone derivatives as CBP/EP300 bromodomain inhibitors for the treatment of castration-resistant prostate cancer. Eur J Med Chem. 2018 Mar 10;147:238-252.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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