5a-Pregnane-3,20-dione
5a-Pregnane-3,20-dione is the endogenous progesterone metabolite.
Product Specifications
CAS Number
[566-65-4]
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H335
Target
Endogenous Metabolite
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Endocrinology; Cancer
Assay Protocol
https://www.medchemexpress.com/5a-Pregnane-3,20-dione.html
Purity
99.76
Solubility
DMSO : 6.67 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
CC([C@H]1CC[C@@]2([H])[C@]3([H])CC[C@@]4([H])CC(CC[C@]4(C)[C@@]3([H])CC[C@]12C)=O)=O
Molecular Formula
C21H32O2
Molecular Weight
316.48
Precautions
H302, H315, H319, H335
References & Citations
[1]Wiebe JP, et al. The endogenous progesterone metabolite, 5a-pregnane-3,20-dione, decreases cell-substrate attachment, adhesion plaques, vinculin expression, and polymerized F-actin in MCF-7 breast cancer cells. Endocrine. 2001 Oct;16 (1) :7-14.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
Human Endogenous Metabolite
Available Sizes
Curated Selection
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