PP5-IN-1
PP5-IN-1 (Compound P053) is a competitive inhibitor of Serine/threonine protein phosphatase-5 (PP5) that binds to its catalytic domain and causes apoptosis in renal cancer[1].
Product Specifications
CAS Number
1022417-69-1
UNSPSC
12352005
Target
Apoptosis; Phosphatase
Type
Reference compound
Related Pathways
Apoptosis; Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/pp5-in-1.html
Purity
99.20
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=S(NC1=CC=C(CC2=CC=CC=C2)C=C1)(C3=C(C)ON=C3C)=O
Molecular Formula
C18H18N2O3S
Molecular Weight
342.41
References & Citations
[1]Elham F Ahanin, et al. Catalytic inhibitor of Protein Phosphatase 5 activates the extrinsic apoptotic pathway by disrupting complex II in kidney cancer. Cell Chem Biol. 2023 Oct 19;30 (10) :1223-1234.e12.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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