CFMS Receptor Inhibitor IV
CFMS Receptor Inhibitor IV (Compound 42) is a potent cFMS inhibitor with an IC50 of 0.017 μM[1].
Product Specifications
CAS Number
[959626-45-0]
UNSPSC
12352005
Hazard Statement
H302-H315-H319
Target
C-Fms
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/cfms-receptor-inhibitor-iv.html
Purity
99.61
Solubility
DMSO : 31.25 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(C1=CC=C(C#N)O1)NC2=CC(N3CCCCC3)=CC=C2N4CCCCC4
Molecular Formula
C22H26N4O2
Molecular Weight
378.47
Precautions
P264-P270-P280-P302+P352-P305+P351+P338-P330-P362+P364-P501
References & Citations
[1]Patch RJ, et al. Potent 2'-aminoanilide inhibitors of cFMS as potential anti-inflammatory agents. Bioorg Med Chem Lett. 2007 Nov 15;17 (22) :6070-4.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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