Ecamsule

Ecamsule is a broad-spectrum UVA filter that can be used in sunscreen product. Ecamsule reduces biological damage caused by solar radiation such as pyrimidine dimer formation, p53 protein accumula-tion, or collagenase 2 expression. Ecamsule has the potential for the research of polymorphous light eruption (PMLE) [1] [2].

Product Specifications

CAS Number

[92761-26-7]

UNSPSC

12352005

Hazard Statement

H318

Target

Biochemical Assay Reagents

Type

Reference compound

Related Pathways

Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/ecamsule.html

Purity

98.02

Solubility

Ethanol : 50 mg/mL (ultrasonic) |Methanol : 31.25 mg/mL (ultrasonic)

Smiles

O=[S](CC(C1=O)(CCC2/C1=C/C(C=C3)=CC=C3/C=C(C4=O)/C(CCC45C[S](=O)(O)=O)C5(C)C)C2(C)C)(O)=O

Molecular Formula

C28H34O8S2

Molecular Weight

562.69

Precautions

H318

References & Citations

[1]Stefanie Hofer, et al. Contradictory effects of chemical filters in UV/ROS-stressed human keratinocyte and fibroblast cells. ALTEX. 2019;36 (2) :231-244.|[2]DeLeo VA, et al. A new ecamsule-containing SPF 40 sunscreen cream for the prevention of polymorphous light eruption: a double-blind, randomized, controlled study in maximized outdoor conditions. Cutis. 2009 Feb;83 (2) :95-103.