Tyrosinase-IN-16

Tyrosinase-IN-16 (compound 19a) is a tyrosine kinase (Tyrosinase) inhibitor with Ki=470 nM. Tyrosinase-IN-16 is cytotoxic to B16F10 cells, with >90% inhibition at 20 μM[1].

Product Specifications

CAS Number

[126651-85-2]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Tyrosinase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/tyrosinase-in-16.html

Purity

98.0

Solubility

DMSO : ≥ 100 mg/mL

Smiles

S=C1NNC(C2=CC=CC(Br)=C2)=N1

Molecular Formula

C8H6BrN3S

Molecular Weight

256.13

Precautions

H302, H315, H319, H335

References & Citations

[1]Choi J, et al. Ensemble-Based Virtual Screening Led to the Discovery of New Classes of Potent Tyrosinase Inhibitors. J Chem Inf Model. 2016 Feb 22;56 (2) :354-67.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, protect from light)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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