UNC-CA2-103
UNC-CA2-103 (compound 128) is a potent inhibitor of Tousled like kinase 2 (TLK2), with the IC50 of 18 nM[1].
Product Specifications
UNSPSC
12352005
Target
Ser/Thr Kinase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/unc-ca2-103.html
Concentration
10mM
Purity
99.26
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
O=C(NC1=CC2=C(NC(/C2=C\C3=C(C)N=CN3)=O)C=C1)C4=CC=CC=C4
Molecular Formula
C20H16N4O2
Molecular Weight
344.37
References & Citations
[1]Jia-Wei Zhang, et al. Discovery and optimization of narrow spectrum inhibitors of Tousled like kinase 2 (TLK2) using quantitative structure activity relationships. Oncol Lett. 2018 Feb;15 (2) :1811-1816.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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