UNC-CA2-103

UNC-CA2-103 (compound 128) is a potent inhibitor of Tousled like kinase 2 (TLK2), with the IC50 of 18 nM[1].

Product Specifications

UNSPSC

12352005

Target

Ser/Thr Kinase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/unc-ca2-103.html

Concentration

10mM

Purity

99.26

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

O=C(NC1=CC2=C(NC(/C2=C\C3=C(C)N=CN3)=O)C=C1)C4=CC=CC=C4

Molecular Formula

C20H16N4O2

Molecular Weight

344.37

References & Citations

[1]Jia-Wei Zhang, et al. Discovery and optimization of narrow spectrum inhibitors of Tousled like kinase 2 (TLK2) using quantitative structure activity relationships. Oncol Lett. 2018 Feb;15 (2) :1811-1816.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

TR315213 1 Kit

RUNDC2B Human shRNA Plasmid Kit (Locus ID 400509)

Ask

View Details

FAB9677JF585 0.1 mL

Human Monoclonal TNF-alpha Antibody (Hu7) [Janelia Fluor 585]

Ask

View Details

NBP1-45682-0.025mg 0.025 mg

Rabbit Polyclonal Lipocalin-2/NGAL Antibody

Ask

View Details

M2749-35-FITC 100 µL

MCM5 (Mini Chromosome Maintenance Protein 5, CDC46, CDC46 Homolog, Cell Division Cycle 46, DNA Replication Licensing Factor MCM5, MGC5315, Minichromosome Maintenance Deficient (S. cerevisiae) 5, Minichromosome Maintenance Deficient Protein 5, P1-CDC46) (FITC)

Ask

View Details

MBS7131574-01 0.1 mL

RAB29 Antibody

Ask

View Details

MBS7131574-02 5x 0.1 mL

RAB29 Antibody

Ask

View Details