Sphingomyelinase from Staphylococcus aureus

<strong>Sphingomyelinase from Staphylococcus aureus</strong>_x000D_ <strong>Catalog number:</strong> B2019701_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 25 units_x000D_ <strong>Molecular Weight or Concentration:</strong> N/A_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> 2-8°C_x000D_ <strong>Keywords:</strong> Sphingomyelin choline phosphohydrolase, Sphingomyelin phosphodiesterase_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Proksch E. pH in nature, humans and skin J Dermatol. 2018 Sep;45(9):1044-1052._x000D_ 2: Krones D, Rühling M, Becker KA, Kunz TC, Sehl C, Paprotka K, Gulbins E, Fraunholz M. Staphylococcus aureus α-Toxin Induces Acid Sphingomyelinase Release From a Human Endothelial Cell Line Front Microbiol. 2021 Jul 29;12:694489._x000D_ 3: Peng H, Li C, Kadow S, Henry BD, Steinmann J, Becker KA, Riehle A, Beckmann N, Wilker B, Li PL, Pritts T, Edwards MJ, Zhang Y, Gulbins E, Grassmé H. Acid sphingomyelinase inhibition protects mice from lung edema and lethal Staphylococcus aureus sepsis J Mol Med (Berl). 2015 Jun;93(6):675-89._x000D_ 4: Becker KA, Fahsel B, Kemper H, Mayeres J, Li C, Wilker B, Keitsch S, Soddemann M, Sehl C, Kohnen M, Edwards MJ, Grassmé H, Caldwell CC, Seitz A, Fraunholz M, Gulbins E. Staphylococcus aureus Alpha-Toxin Disrupts Endothelial-Cell Tight Junctions via Acid Sphingomyelinase and Ceramide Infect Immun. 2017 Dec 19;86(1):e00606-17._x000D_ 5: Ma J, Gulbins E, Edwards MJ, Caldwell CC, Fraunholz M, Becker KA. Staphylococcus aureus α-Toxin Induces Inflammatory Cytokines via Lysosomal Acid Sphingomyelinase and Ceramides Cell Physiol Biochem. 2017;43(6):2170-2184._x000D_ 6: Freer JH, Arbuthnott JP. Toxins of Staphylococcus aureus Pharmacol Ther. 1982;19(1):55-106._x000D_ 7: Jia Y, Guan Z, Liu C, Huang M, Li J, Feng J, Shen B, Yang G. Staphylococcus aureus β-hemolysin causes skin inflammation by acting as an agonist of epidermal growth factor receptor Microbiol Spectr. 2024 Jan 11;12(1):e0222723._x000D_ 8: Kaveemongkonrat S, Duangsonk K, Houbraken J, Suwannaphong P, Vanittanakom N, Mekaprateep M. Partial characteristics of hemolytic factors secreted from airborne Aspergillus and Penicillium, and an enhancement of hemolysis by Aspergillus micronesiensis CAMP-like factor via Staphylococcus aureus-sphingomyelinase J Microbiol. 2019 Dec;57(12):1086-1094._x000D_ 9: Rohmer C, Wolz C. The Role of hlb-Converting Bacteriophages in Staphylococcus aureus Host Adaption Microb Physiol. 2021;31(2):109-122._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/39505263">10: Zhou B, Pathania A, Pant D, Halpern D, Gaudu P, Trieu-Cuot P, Dias-Leao A, Pagot C, Solgadi A, Gruss A, Gloux K. Prophages divert Staphylococcus aureus defenses against host lipids J Lipid Res. 2024 Dec;65(12):100693. </a>_x000D_ _x000D_ <strong>Products Related to Sphingomyelinase from Staphylococcus aureus can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>