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CD79B, Rat (HEK293, His)

Product Specifications

UNSPSC Description

CD79B Protein, also known as B29 or Igβ, is an essential component of the B cell receptor along with immunoglobulin and mb1 (Igα, CD79a) and is absolutely required for B cell development. Rat CD79B protein comprises 228 amino acids, and its amino acid sequence is 85 and 69% identical with the mouse and human counterparts, respectively. The B-cell antigen receptor (BCR) signaling component Igβ (CD79B) and the co-receptor CD19 act as an alternative B-cell signaling module that promotes the survival of B lymphoma and normal B cells via integrated ITAM/PI3K signaling. The loss of CD79B causes a block in N-glycan maturation and accumulation of immature proteins[1][2][3]. CD79B Protein, Rat (HEK293, His) is the recombinant rat-derived CD79B protein, expressed by HEK293 , with C-His labeled tag. The total length of CD79B Protein, Rat (HEK293, His) is 133 a.a., with molecular weight of 25-30 kDa.

Type

Recombinant Proteins

Assay Protocol

https://www.medchemexpress.com/cytokines/cd79b-protein-rat-hek293-his.html

Purity

98.00

Smiles

VPAMTKSDQP PIFQGSPCSK IWQHPRFAAK KRSSMVKFHC HTDYSGVMTW FRQKGNQRPQ ELFPEDGHIS QTRNGSVYTL TLQNIQYEDN GIYFCQQKCN STEPDVTDGC GTELLVLGFS TLDQLKRRNT LKD

Molecular Weight

Approximately 25-30 kDa due to the glycosylation.

Shipping Conditions

Blue Ice

Storage Conditions

Stored at -20°C for 2 years

Available Sizes

Curated Selection

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