Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

BOC-D-FMK

Boc-D-FMK is a cell-permeable, irreversible and broad spectrum caspase inhibitor. Boc-D-FMK inhibits apoptosis stimulated by TNF-α with an IC50 of 39 μM.

Product Specifications

CAS Number

634911-80-1

UNSPSC

12352211

Target

Apoptosis; Caspase

Type

Reference compound

Related Pathways

Apoptosis

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/BOC-D-FMK.html

Purity

95.0

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(CC(C(CF)=O)NC(OC(C)(C)C)=O)OC

Molecular Formula

C11H18FNO5

Molecular Weight

263.26

References & Citations

[1]Cowburn AS, et al. z-VAD-fmk augmentation of TNF alpha-stimulated neutrophil apoptosis is compound specific and does not involve the generation of reactive oxygen species.|[2]Yee SB, et al. zVAD-fmk, unlike BocD-fmk, does not inhibit caspase-6 acting on 14-3-3/Bad pathway in apoptosis of p815 mastocytoma cells. Exp Mol Med. 2006 Dec 31;38 (6) :634-42.|[3]Sheen-Chen SM, et al. Effect of Boc-D-Fmk on hepatocyte apoptosis after bile duct ligation in rat and survival rate after endotoxin challenge. J Gastroenterol Hepatol. 2008 Aug;23 (8 Pt 1) :1276-9.|[4]Chan YM, et al. Inhibition of caspases promotes long-term survival and reinnervation by axotomized spinal motoneurons of denervated muscle in newborn rats. Exp Neurol. 2003 Jun;181 (2) :190-203.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

Caspase

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

Egr3 3'UTR GFP Stable Cell Line
TU155672 1.0 mL

Egr3 3'UTR GFP Stable Cell Line

Sign In for Pricing
View Details
Phospho-Jak1 (Tyr1034 + Tyr1035) Polyclonal Antibody, AbBy Fluor™ 750 Conjugated
bs-3238R-BF750-TR 20 µL

Phospho-Jak1 (Tyr1034 + Tyr1035) Polyclonal Antibody, AbBy Fluor™ 750 Conjugated

Sign In for Pricing
View Details
Nothobranchius furzeri LOC107376698 Rabbit Polyclonal Antibody (APC)
orb2805811 200 µL

Nothobranchius furzeri LOC107376698 Rabbit Polyclonal Antibody (APC)

Sign In for Pricing
View Details
Chicken Anti-phosphatidyl serine antibody (APSA) ELISA Kit
MBS261152-01 48 Well

Chicken Anti-phosphatidyl serine antibody (APSA) ELISA Kit

Sign In for Pricing
View Details
Chicken Anti-phosphatidyl serine antibody (APSA) ELISA Kit
MBS261152-02 96 Well

Chicken Anti-phosphatidyl serine antibody (APSA) ELISA Kit

Sign In for Pricing
View Details
Chicken Anti-phosphatidyl serine antibody (APSA) ELISA Kit
MBS261152-03 5x 96 Well

Chicken Anti-phosphatidyl serine antibody (APSA) ELISA Kit

Sign In for Pricing
View Details