MeIQx
MeIQx, a dietary aromatic amine, is mutagenic compound could be isolated from present in fried beef and beef extracts. MeIQx binds covalently to hemoglobin. MeIQx induces liver tumors[1][2].
Product Specifications
CAS Number
77500-04-0
Product Name Alternative
2-Amino-3,8-dimethylimidazo[4,5-f]quinoxaline-2
UNSPSC
12352005
Hazard Statement
H341, H351
Target
Cytochrome P450
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/meiqx.html
Purity
99.0
Solubility
H2O : 0.71 mg/mL (ultrasonic; adjust pH to 5 with HCl)
Smiles
N1=CC(=NC2=C1C=CC3=C2N=C(N)N3C)C
Molecular Formula
C11H11N5
Molecular Weight
213.24
Precautions
H341, H351
References & Citations
[1]Lynch AM, et, al. The measurement of MeIQx adducts with mouse haemoglobin in vitro and in vivo: implications for human dosimetry. Carcinogenesis. 1991 Jun;12 (6) :1067-72.|[2]Ohgaki H, et, al. Carcinogenicity in mice of a mutagenic compound, 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx) from cooked foods. 1987 May;8 (5) :665-8.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
Phase 1
Available Sizes
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