MeIQx

MeIQx, a dietary aromatic amine, is mutagenic compound could be isolated from present in fried beef and beef extracts. MeIQx binds covalently to hemoglobin. MeIQx induces liver tumors[1][2].

Product Specifications

CAS Number

[77500-04-0]

Product Name Alternative

2-Amino-3,8-dimethylimidazo[4,5-f]quinoxaline-2

UNSPSC

12352005

Hazard Statement

H341, H351

Target

Cytochrome P450

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/meiqx.html

Purity

99.0

Solubility

H2O : 0.71 mg/mL (ultrasonic; adjust pH to 5 with HCl)

Smiles

N1=CC(=NC2=C1C=CC3=C2N=C(N)N3C)C

Molecular Formula

C11H11N5

Molecular Weight

213.24

Precautions

H341, H351

References & Citations

[1]Lynch AM, et, al. The measurement of MeIQx adducts with mouse haemoglobin in vitro and in vivo: implications for human dosimetry. Carcinogenesis. 1991 Jun;12 (6) :1067-72.|[2]Ohgaki H, et, al. Carcinogenicity in mice of a mutagenic compound, 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx) from cooked foods. 1987 May;8 (5) :665-8.