11-Hydroxycanthin-6-one
11-Hydroxycanthin-6-one, a canthin-6-one (HY-N3536) alkaloid, is an antitumor agent which shows potent cytotoxic activity[1][2].
Product Specifications
CAS Number
[75969-83-4]
UNSPSC
12352005
Hazard Statement
H302-H312-H332
Target
Drug Derivative
Type
Natural Products
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/11-hydroxycanthin-6-one.html
Solubility
10 mM in DMSO
Smiles
O=C1N2C3=C(N=CC=C3C4=C2C=CC=C4O)C=C1
Molecular Formula
C14H8N2O2
Molecular Weight
236.23
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P363-P501
References & Citations
[1]Fukamiya N, et, al. Antitumor agents: LXXXVII. Cytotoxic antileukemic canthin-6-one alkaloids from Brucea antidysenterica and the structure activity relationships of their related derivatives. Planta Med. 1987 Apr;53 (2) :140-3.|[2]Miyake K, et, al. Canthin-6-one alkaloids and a tirucallanoid from Eurycoma longifolia and their cytotoxic activity against a human HT-1080 fibrosarcoma cell line. Nat Prod Commun. 2010 Jan;5 (1) :17-22.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-116786/11-Hydroxycanthin-6-one-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-116786/
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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