PF-DcpSi
PF-DcpSi is a mRNA decapping scavenger enzyme (DcpS) inhibitor (IC50: 0.11 nM) . PF-DcpSi (30 mg/kg, i.p.) ameliorates the disease phenotype in a mice model of spinal muscular atrophy (SMA) [1].
Product Specifications
UNSPSC
12352005
Target
DNA/RNA Synthesis
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/pf-dcpsi.html
Purity
98.0
Smiles
N#CC1=CC(F)=CC(OCC2=CC=CC3=NC(N)=NC(N)=C23)=C1
Molecular Formula
C16H12FN5O
Molecular Weight
309.30
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-122604/PF-DcpSi-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-122604/PF-DcpSi-SDS-MedChemExpress.pdf
Scientific Category
Reference compound1
Clinical Information
Phase 1
CAS Number
[2092917-19-4]
Available Sizes
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