Methysticin

Methysticin is a major kavalactone in kava extract to induce CYP1A1.

Product Specifications

CAS Number

[20697-20-5]

Product Name Alternative

DL-Methysticin; (±) -Methystici

UNSPSC

12352005

Target

Cytochrome P450

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/Methysticin.html

Solubility

10 mM in DMSO

Smiles

O=C1C=C(OC)CC(/C=C/C2=CC=C(OCO3)C3=C2)O1

Molecular Formula

C15H14O5

Molecular Weight

274.27

References & Citations

[1]Li Y, et al. Methysticin and 7,8-dihydromethysticin are two major kavalactones in kava extract to induce CYP1A1. Toxicol Sci. 2011 Dec;124 (2) :388-99.|[2]Fragoulis A, et al. Oral administration of Methysticin improves cognitive deficits in a mouse model of Alzheimer's disease. Redox Biol. 2017 Aug;12:843-853.