Cefazedone

Cefazedone (Refosporen) is a first-generation cephalosporin antibiotic. Cefazedone is active against both Gram-positive and Gram-negative bacteria[1][2].

Product Specifications

CAS Number

[56187-47-4]

Product Name Alternative

Refosporen

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Antibiotic; Bacterial

Type

Natural Products

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/cefazedone.html

Purity

99.89

Solubility

DMSO : 116.67 mg/mL (ultrasonic)

Smiles

O=C(O)C(N1[C@@]([H])([C@@H](C1=O)NC(CN(C=C(C2=O)Cl)C=C2Cl)=O)SC3)=C3CSC4=NN=C(S4)C

Molecular Formula

C18H15Cl2N5O5S3

Molecular Weight

548.44

Precautions

H302, H315, H319, H335

References & Citations

[1]Gao L, et al. A Pharmacokinetic and Pharmacodynamic Study on Intravenous Cefazedone Sodium in Patients with Community-acquired Pneumonia. Chin Med J (Engl) . 2015 May 5;128 (9) :1160-4.|[2]Bloom JC, et al. Cephalosporin-induced immune cytopenia in the dog: demonstration of erythrocyte-, neutrophil-, and platelet-associated IgG following treatment with cefazedone. Am J Hematol. 1988 Jun;28 (2) :71-8.