For-Met-OH

For-Met-OH (N-Formylmethionine) can be involved in the translation process of bacteria, chloroplasts, and mitochondria. For-Met-OH plays different roles in different species and organelles, such as promoting the formation of protein complexes in mitochondria and acting as a degradation signal in bacteria and yeast. The level of For-Met-OH is closely related to certain diseases, for example, For-Met-OH is a potential biomarker for metabolic disorders and poor prognosis in critically ill patients[1][2][3].

Product Specifications

CAS Number

[4289-98-9]

Product Name Alternative

N-Formylmethionine

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H335

Target

Bacterial; Endogenous Metabolite

Type

Natural Products

Related Pathways

Anti-infection; Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Infection; Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/for-met-oh.html

Purity

99.92

Solubility

DMSO : 100 mg/mL (ultrasonic) |H2O : 50 mg/mL (ultrasonic)

Smiles

CSCC[C@@H](C(O)=O)NC=O

Molecular Formula

C6H11NO3S

Molecular Weight

177.22

Precautions

H302, H315, H319, H335

References & Citations

[1]Lee CS, et al. Where Does N-Formylmethionine Come from? What for? Where Is It Going? What is the origin of N-formylmethionine in eukaryotic cells? Mol Cells. 2022 Mar 31;45 (3) :109-111.|[2]Sigurdsson MI, et al. Circulating N-formylmethionine and metabolic shift in critical illness: a multicohort metabolomics study. Crit Care. 2022 Oct 19;26 (1) :321.|[3]Feng Y, et al. The major role of Listeria monocytogenes folic acid metabolism during infection is the generation of N-formylmethionine. mBio. 2023 Oct 31;14 (5) :e0107423.