Lyn Recombinant Rabbit Monoclonal Antibody [JE44-75]
Tyrosine-protein kinase Lyn is a protein that in humans is encoded by the LYN gene. Lyn is a member of the Src family of protein tyrosine kinases, which is mainly expressed in hematopoietic cells, in neural tissues liver, and adipose tissue. In various hematopoietic cells, Lyn has emerged as a key enzyme involved in the regulation of cell activation. In these cells, a small amount of LYN is associated with cell surface receptor proteins, including the B cell antigen receptor (BCR), CD40, or CD19. The abbreviation Lyn is derived from Lck/Yes novel tyrosine kinase, Lck and Yes also being members of the Src kinase family.
Product Specifications
CAS Number
9000-83-3
Product Name Alternative
Abbreviation
LYN, JTK8
Swiss Prot
P07948 Human, P25911 Mouse, Q07014 Rat
Cellular Locus
Cell membrane, Nucleus, Cytoplasm, perinuclear region, Golgi apparatus, Membrane.
Host
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Synthetic peptide within Human Lyn aa 1-100.
Isotype
IgG
Clone
JE44-75
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, FC
Positive Control
Concentration
1 mg/mL
Dilution
WB: 1:1,000-1:2,000 ;FC: 1:1,000
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 59 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes
Frequently Asked Questions
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