SIRT2-IN-12
SIRT2-IN-12 (Compound 3) is a SIRT2 inhibitor with a IC50 value of 50 μM[1].
Product Specifications
UNSPSC
12352005
Target
Sirtuin
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/sirt2-in-12.html
Solubility
10 mM in DMSO
Smiles
O=C1C2=C(OC3=C1C=CC=C3Cl)C=CC(CNCCC4=CC=CC=C4OC)=C2.Cl
Molecular Formula
C23H21Cl2NO3
Molecular Weight
430.32
References & Citations
[1]Mazur G, et al. Novel xanthone derivatives as potent sirtuin 2 inhibitors. Bioorg Med Chem Lett. 2024 Mar 1;100:129620.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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