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SIRT2-IN-12

SIRT2-IN-12 (Compound 3) is a SIRT2 inhibitor with a IC50 value of 50 μM[1].

Product Specifications

UNSPSC

12352005

Target

Sirtuin

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage; Epigenetics

Applications

Cancer-programmed cell death

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/sirt2-in-12.html

Solubility

10 mM in DMSO

Smiles

O=C1C2=C(OC3=C1C=CC=C3Cl)C=CC(CNCCC4=CC=CC=C4OC)=C2.Cl

Molecular Formula

C23H21Cl2NO3

Molecular Weight

430.32

References & Citations

[1]Mazur G, et al. Novel xanthone derivatives as potent sirtuin 2 inhibitors. Bioorg Med Chem Lett. 2024 Mar 1;100:129620.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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