Flavoxate-d4 (hydrochloride)
Flavoxate-d4 hydrochloride (Rec-7-0040-d4) is the deuterium labeled Flavoxate hydrochloride. Flavoxate Hydrochloride is a muscarinic AChR antagonist used in various urinary syndromes and as an antispasmodic[1][2].
Product Specifications
CAS Number
1189678-43-0
UNSPSC
12352005
Target
Isotope-Labeled Compounds; mAChR
Type
Isotope-Labeled Compounds
Related Pathways
GPCR/G Protein; Neuronal Signaling; Others
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Solubility
10 mM in DMSO
Smiles
C(OC(C(N1CCCCC1)([2H])[2H])([2H])[2H])(=O)C2=C3C(C(=O)C(C)=C(O3)C4=CC=CC=C4)=CC=C2.Cl
Molecular Formula
C24H22D4ClNO4
Molecular Weight
431.95
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.|[2]Dansette, P.M., et al. HMG-CoA reductase activity in human liver microsomes: comparative inhibition by statins. Exp Toxicol Pathol, 2000. 52 (2) : p. 145-8.|[3]Kimura, Y., et al., Mechanisms of the suppression of the bladder activity by flavoxate. Int J Urol, 1996. 3 (3) : p. 218-27.|[4]Oka, M., et al., Brain pertussis toxin-sensitive G proteins are involved in the flavoxate hydrochloride-induced suppression of the micturition reflex in rats. Brain Res, 1996. 727 (1-2) : p. 91-8.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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