Remisporine B
Remisporine B is a polyketide, that can be isolated from Penicillium sp. ZJ-SY2. Remisporine B exhibits immunosuppressive efficacy, that inhibits concanavalin A -induced T-cell proliferation and LPS (HY-D1056) - induced B-cell proliferations of mouse splenic lymphocytes with IC50 of 30.1 µg/mL and 32.4 µg/mL[1].
Product Specifications
CAS Number
571194-06-4
UNSPSC
12352005
Target
Endogenous Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/remisporine-b.html
Smiles
COC([C@]12[C@]3([H])[C@](C4=C(OC5=CC(C)=CC(O)=C5C4=O)C[C@@]3([H])[C@](O)(O2)C(OC)=O)([H])C6=C1C(C7=C(O)C=C(C)C=C7O6)=O)=O
Molecular Formula
C30H24O12
Molecular Weight
576.50
References & Citations
[1]Liu H, et al., Polyketides with Immunosuppressive Activities from Mangrove Endophytic Fungus Penicillium sp. ZJ-SY₂. Mar Drugs. 2016 Nov 25;14 (12) :217.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
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