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MRS 2219

MRS 2219 (Pyridoxol) is a selective pharmacological probe of P2X1 receptor. MRS 2219 selectively potentiated ATP-evoked responses at P2X1 receptors with an EC50 of 5.9 μM[1].

Product Specifications

CAS Number

14141-47-0

Product Name Alternative

Pyridoxol, cyclic 3,4- (hydrogen phosphate)

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

P2X Receptor

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/mrs-2219.html

Smiles

O=P1(OCC2=CN=C(C)C(O)=C2CO1)O

Molecular Formula

C8H10NO5P

Molecular Weight

231.14

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Jacobson KA, et al. A pyridoxine cyclic phosphate and its 6-azoaryl derivative selectively potentiate and antagonize activation of P2X1 receptors. J Med Chem. 1998 Jun 18;41 (13) :2201-6.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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