6-Methyluracil

6-Methyluracil (Pseudothymine), a metabolite of Uracil, can be used as an indicator of acetoacetyl-CoA (AACoA) accumulation. 6-Methyluracil exhibits antiradiation effect in vivo[1][2].

Product Specifications

CAS Number

[626-48-2]

Product Name Alternative

Pseudothymine

UNSPSC

12352005

Hazard Statement

H361

Target

Endogenous Metabolite

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/6-methyluracil.html

Purity

99.69

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

O=C1NC(C=C(C)N1)=O

Molecular Formula

C5H6N2O2

Molecular Weight

126.11

Precautions

H361

References & Citations

[1]Cromby CH, et, al. 6-Methyluracil excretion in 2-methylacetoacetyl-CoA thiolase deficiency and in two children with an unexplained recurrent ketoacidaemia. J Inherit Metab Dis. 1994;17 (1) :81-4.|[2]Taran IP, et, al. [The antiradiation action of 6-methyluracil]. Radiobiologiia. Mar-Apr 1993;33 (2) :285-90.